MyBioSource.com's Mouse Anti-SLC9A3R1 / NHERF1 / EBP50 Antibody is a Mouse monoclonal antibody. The Mouse Anti-SLC9A3R1 / NHERF1 / EBP50 Antibody was generated using SLC9A3 regulator 1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Members of the ezrin-radixin-moesin (ERM) protein family are highly concentrated in the apical aspect of polarized epithelial cells. These cells are studded with microvilli containing bundles of actin filaments, which must attach to the membrane to assemble and maintain the microvilli. The ERM proteins, together with merlin, the NF2 gene product, are thought to be linkers between integral membrane and cytoskeletal proteins, and they bind directly to actin in vitro